Still, some amigos never returned (4,2)
I believe the answer is:
even so
'still' is the definition.
(both can mean 'nonetheless')
'some amigos never returned' is the wordplay.
'some' says the answer is hidden in the clue (some of the parts of the word are used).
'returned' is a reversal indicator.
'osneve' is hidden within 'amigos never'.
'osneve' in reverse letter order is 'EVEN SO'.
(Other definitions for even so that I've seen before include "however" , "Despite that, nevertheless" , "Just the same, though that may be the case" , "Although that is the case, nevertheless" , "'In spite of that (4,2)'" .)