Stoical stout girl’s spasmodic twitching (10)
I believe the answer is:
fatalistic
'stoical' is the definition.
(both can mean resigned to events)
'stout girl's spasmodic twitching' is the wordplay.
'stout' becomes 'fat' (similar in meaning).
'girl's' becomes 'Ali's' (girl's name).
'spasmodic twitching' becomes 'tic' (an involuntary twitch).
'fat'+'alis'+'tic'='FATALISTIC'
(Other definitions for fatalistic that I've seen before include "Believing in predestination" , "Accepting lot" , "Resigned" .)