Stoma (hole after surgery) is disgusting (9)
I believe the answer is:
loathsome
'is disgusting' is the definition.
(synonyms)
'stoma hole after surgery' is the wordplay.
'after surgery' indicates anagramming the letters.
'stoma'+'hole'='stomahole'
'stomahole' anagrammed gives 'LOATHSOME'.
(Other definitions for loathsome that I've seen before include "Horrid" , "Detestable" , "Hateful" , "Disgusting, nauseating" , "Repulsive" .)