Stop runs from part of wicket (5)
I believe the answer is:
cease
'stop' is the definition.
(I know that stop can be written as cease)
'runs from part of wicket' is the wordplay.
'runs' becomes 'r' (cricket abbreviation).
'from' suggests deleting specific letters.
'part of wicket' becomes 'crease' (cricket).
'crease' with 'r' taken out is 'CEASE'.
(Other definitions for cease that I've seen before include "Stop, give over" , "Finish, end" , "Come to an end" , "Culminate" , "Stop, finish" .)