Stopper of drink twisted (4)
I believe the answer is:
plug
'stopper' is the definition.
(I know that plug is a type of stopper)
'drink twisted' is the wordplay.
'drink' becomes 'gulp' (gulping is a kind of drinking).
'twisted' says the letters should be written backwards.
'gulp' written backwards gives 'PLUG'.
'of' acts as a link.
(Other definitions for plug that I've seen before include "Stopper - advert" , "Device put into socket" , "Wad, of tobacco say" , "Blatant promotion" , "Stopper - advertisement" .)