Strange story about Eastern seafood (6)
I believe the answer is:
oyster
'seafood' is the definition.
(oyster is a kind of seafood)
'strange story about eastern' is the wordplay.
'strange' indicates anagramming the letters.
'about' is an insertion indicator.
'eastern' becomes 'e'.
'story' is an anagram of 'oystr'.
'oystr' going around 'e' is 'OYSTER'.
(Other definitions for oyster that I've seen before include "Shellfish (maybe the world!)" , "Flat shellfish" , "the world may be yours" , "World as place of opportunity" , "Capital card" .)