Strangely, loco's hard to start for train (6)
I believe the answer is:
school
'for train' is the definition.
(both can mean to teach or coach)
'strangely loco's hard to start' is the wordplay.
'strangely' indicates an anagram.
'to start' indicates taking the first letters.
The initial letter of 'hard' is 'h'.
'locos'+'h'='locosh'
'locosh' is an anagram of 'SCHOOL'.
(Other definitions for school that I've seen before include "See 7" , "Institute of education" , "these like-minded people could follow" , "Teach - fishes swimming" , "Teach; group of fish" .)