Strangers getting jiggy with soprano might do this (10)
I believe the answer is:
transgress
'might do this' is the definition.
The definition suggests a singular noun but the answer is not.
'strangers getting jiggy with soprano' is the wordplay.
I cannot really see how this works, but
an anagram of 'strangers' is 'transgres' which is located in the answer.
'soprano' could be 's' (musical abbreviation) and 's' is found within the answer.
No letters remain.
This explanation may well be incorrect...
Can you help me to learn more?
(Other definitions for transgress that I've seen before include "Cause offence" , "commit offence" , "Break (limit, law)" , "Overstep, exceed" , "Commit a sin" .)