Strap human essentially in a state of shock (6)
I believe the answer is:
trauma
'strap human' is the definition.
Although both the answer and definition are singular nouns, I can't understand how they can define each other.
'essentially in a state of shock' is the wordplay.
'essentially' says to take the centre.
'in a state' becomes 'distraught' (I've seen this before).
'of shock' becomes 'ma' (I am not sure about this - if you are sure you should give a lot more credence to this answer).
The middle of 'distraught' is 'trau'.
'trau'+'ma'='TRAUMA'
Can you help me to learn more?
(Other definitions for trauma that I've seen before include "Nervous shock" , "hurt" , "Lasting shock or disturbance" , "Severe shock, injury" , "Shock to the body or mind" .)