Strike during scuffle (4)
I believe the answer is:
cuff
'strike' is the definition.
(I've seen this before)
'during scuffle' is the wordplay.
'during' indicates the answer is hidden within the clue.
'CUFF' is hidden in the letters of 'scuffle'.
(Other definitions for cuff that I've seen before include "There may be a link with this" , "Part of garment covering wrist" , "End part of sleeve" , "A slap" , "by one hand" .)