Strikers in this game come to blows (8)
I believe the answer is:
matchbox
'strikers in this' is the definition.
The definition suggests a singular noun which matches the answer.
'game come to blows' is the wordplay.
'game' becomes 'match' (I've seen this before).
'come to blows' becomes 'box' (I can't justify this - if you can you should believe this answer much more).
'match'+'box'='MATCHBOX'
Can you help me to learn more?
(Other definitions for matchbox that I've seen before include "Container for lighters" , "This will hold your vestas" , "Small" , "in which strikers are contained" , "that has inflammable contents?" .)