Strike's ending: Unite creates issue (6)
I believe the answer is:
emerge
'issue' is the definition.
(issue can mean to emerge or appear)
'strike's ending unite' is the wordplay.
'ending' says to take the final letters (the ending of the word).
'unite' becomes 'merge' (synonyms).
The final letter of 'strike' is 'e'.
'e'+'merge'='EMERGE'
'creates' acts as a link.
(Other definitions for emerge that I've seen before include "Develop" , "Become known or apparent" , "Come into greater prominence" , "Suddenly appear" , "Materialize" .)