Strongman holds one great artist (6)
I believe the answer is:
titian
'great artist' is the definition.
'Titian' can be an answer for 'artist' (16th-century painter). I am not sure about the 'great' bit.
'strongman holds one' is the wordplay.
'strongman holds' becomes 'titi' (I am not sure about this - if you are sure you should give a lot more credence to this answer).
'one' becomes 'an' (an apple is one apple).
'titi'+'an'='TITIAN'
Can you help me to learn more?
(Other definitions for titian that I've seen before include "Italian painter, d. 1576" , "artist from Venice" , "He painted" , "Italian Old Master and colour" , "Sixteenth century Venetian painter" .)