Stubborn person has something afoot (4)
I believe the answer is:
mule
'stubborn person' is the definition.
(I've seen this in another clue)
I can't explain the rest of the clue.
Can you help me to learn more?
(Other definitions for mule that I've seen before include "Sterile offspring of donkey and horse" , "Drug smuggler" , "Donkey-horse hybrid" , "Proverbially stubborn beast" , "Drug courier; animal" .)