Stuck inside, catch a fever and become irritated (5)
I believe the answer is:
chafe
'stuck inside' is the definition.
Although both the answer and definition are singular nouns, I don't see how they can define each other.
'catch a fever and become irritated' is the wordplay.
'CHAFE' is hidden in amongst the letters.
But, I'm unsure how this is indicated.
Can you help me to learn more?
(Other definitions for chafe that I've seen before include "Wear away by rubbing" , "Fray" , "feel irritated" , "Fret" , "are galling" .)