Study up with Ned (3)
I believe the answer is:
den
'study' is the definition.
(I've seen this before)
'up with ned' is the wordplay.
'ned' anagrams to 'DEN'.
Though, I'm not sure how the anagram is indicated.
Can you help me to learn more?
(Other definitions for den that I've seen before include "Room for work or play" , "Animal's lair or gent's study" , "Wild animal's home" , "Miserable place" , "Hiding place" .)