Succeeded with wine brewed for strength (5)
I believe the answer is:
sinew
'for strength' is the definition.
(sinew is a kind of strength)
'succeeded with wine brewed' is the wordplay.
'succeeded' becomes 's' (genealogical abbreviation).
'with' says to put letters next to each other.
'brewed' indicates an anagram.
'wine' with letters rearranged gives 'inew'.
's'+'inew'='SINEW'
(Other definitions for sinew that I've seen before include "Strength; tendon" , "Tough material" , "It indicates strength" , "As synonym for 'strength'" , "Cord of tissue connecting muscle to bone" .)