Such a destination includes Pluto (5)
I believe the answer is:
hades
'pluto' is the definition.
('Hades' can be a synonym of 'pluto')
'such a destination includes' is the wordplay.
'includes' says the answer is hidden in the clue.
'HADES' is hidden in the letters of 'such a destination'.
(Other definitions for hades that I've seen before include "In Greek myth, the Underworld" , "Underworld, hell" , "The nether world, hell" , "Greek god of the underworld" , "Hell of Greek myth" .)