Such people have little in common (13)
I believe the answer is:
disadvantaged
'common' is the definition.
(thesaurus)
I can't explain the rest of the clue.
Can you help me to learn more?
(Other definitions for disadvantaged that I've seen before include "underprivileged" , "Socially or economically deprived" , "Put in an unfavourable position" , "In unfavourable circumstances" , "Handicapped" .)