Suffer in main current (5)
I believe the answer is:
incur
'suffer' is the definition.
(to incur is to suffer or experience)
'in main current' is the wordplay.
'in' says the answer is hidden in the clue.
'INCUR' is hidden in the letters of 'main current'.
(Other definitions for incur that I've seen before include "Attract" , "Bring on oneself, probably unpleasant" , "Become liable to (eg, a penalty)" , "Bring something on oneself, often unpleasant" , "Arouse" .)