Supremely evil influence in Chartist reforms (10)
I believe the answer is:
antichrist
'supremely evil influence' is the definition.
'in chartist reforms' is the wordplay.
'reforms' indicates an anagram.
'in'+'chartist'='inchartist'
'inchartist' with letters rearranged gives 'ANTICHRIST'.
(Other definitions for antichrist that I've seen before include "religious foe" , "Opponent of Jesus" .)
I've seen this clue in The Guardian, The Times and The Telegraph.
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