Susie produces children (5)
I believe the answer is:
issue
'children' is the definition.
(issue can mean someone's offspring)
'susie produces' is the wordplay.
'produces' indicates anagramming the letters.
'susie' with letters rearranged gives 'ISSUE'.
(Other definitions for issue that I've seen before include "Spring - children - publication" , "Hot topic; outcome" , "Important problem" , "Important topic for offspring" , "Bring out - children" .)