Susie's unruly brood (5)
I believe the answer is:
issue
'brood' is the definition.
(thesaurus)
'susie's unruly' is the wordplay.
'unruly' indicates an anagram.
'susie' with letters rearranged gives 'ISSUE'.
(Other definitions for issue that I've seen before include "Offspring; publish" , "Instalment" , "Children; topic for debate" , "Problem - child" , "hot potato?" .)