Suspicion burglar's first about at hotel (6)
I believe the answer is:
breath
'suspicion' is the definition.
(I've seen this in other clues)
'burglar's first about at hotel' is the wordplay.
'burglar's first' becomes 'b' (rst letter of 'burglar').
'about' becomes 're' ('re' means regarding or about).
'hotel' becomes 'h' (phonetic alphabet: alpha, bravo, charlie etc.).
'b'+'re'+'at'+'h'='BREATH'
(Other definitions for breath that I've seen before include "Respiration" , "Save your ...... - refrain from useless discussion" , "Bather (anag.)" , "Air received and expelled" , "Air in an out of the lungs" .)