Swap roles with no-hoper (5)
I believe the answer is:
loser
'no-hoper' is the definition.
(I've seen this before)
'swap roles' is the wordplay.
'swap' is an anagram indicator (I've seen 'swaps' mean this).
'roles' with letters rearranged gives 'LOSER'.
'with' acts as a link.
(Other definitions for loser that I've seen before include "One failing regularly" , "Defeated person" , "Unsuccessful contestant" , "Proverbially, one who hesitates" , "One mislaying" .)