Symptom of myalgic encephalomyelitis and long Covid (9)

I believe the answer is:

tiredness

(Other definitions for tiredness that I've seen before include "Weary feeling" , "That's liable to occur at midnight" , "Lassitude; residents (anag.)" , "Exhaustion" , "7 (anag)" .)

I've seen this clue in The Times and The Sunday Times.

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