'T isn't corrupt (5)
I believe the answer is:
taint
'corrupt' is the definition.
(I've seen this before)
''t isn't' is the wordplay.
'isn't' becomes 'aint' (I've seen this before).
't'+'aint'='TAINT'
(Other definitions for taint that I've seen before include "Contaminate, pollute" , "Blemish" , "contaminant" , "Adulterate" , "Defect - contamination" .)