Tactics Harpo contrived with dire outcome (12)
I believe the answer is:
catastrophic
'tactics harpo contrived with dire outcome' is the definition.
I can't judge whether this definition defines the answer.
'tactics harpo contrived' is the wordplay.
'contrived' indicates an anagram.
'tactics'+'harpo'='tacticsharpo'
'tacticsharpo' anagrammed gives 'CATASTROPHIC'.
Can you help me to learn more?
(Other definitions for catastrophic that I've seen before include "Disastrous" , "Chaotic parts (anag)" , "Causing sudden damage" , "Extremely unfortunate" .)