Take a chance on body-search with top off (4)
I believe the answer is:
risk
'take a chance' is the definition.
('risk' can be a synonym of 'take a chance')
I don't understand the remainder of the clue.
Can you help me to learn more?
(Other definitions for risk that I've seen before include "Gamble" , "Assessment of potential dangers -- any silk saris (anag)" , "The possibility of danger - chance it" , "Endanger, jeopardise" , "Possibility of bad outcome" .)