Take a chance with Blackpool's outsiders in match (6)
I believe the answer is:
gamble
'take a chance' is the definition.
(synonyms)
'blackpool's outsiders in match' is the wordplay.
'outsiders' suggests removing the centre (only the letters on the outside of the word remain).
'in' is an insertion indicator.
'match' becomes 'game' (I've seen this before).
'blackpool' with its centre removed is 'bl'.
'bl' inserted within 'game' is 'GAMBLE'.
'with' is the link.
(Other definitions for gamble that I've seen before include "Take risks" , "Take a chance, speculate" , "Make a bet" , "punt" , "Run a risk" .)