Take exception to Sterne novel (6)
I believe the answer is:
resent
'take exception to' is the definition.
(I've seen this before)
'sterne novel' is the wordplay.
'novel' indicates an anagram (letters in a new or novel order).
'sterne' anagrammed gives 'RESENT'.
(Other definitions for resent that I've seen before include "Don't like" , "Feel bitter or indignant about" , "Nurse bitter or angry feeling" , "Feel displeased or indignant about" , "Dislike" .)