Take flight affected by delays, losing deposits (6)
I believe the answer is:
decamp
'take flight' is the definition.
(decamping is a kind of taking flight)
'affected by delays losing deposits' is the wordplay.
'affected' becomes 'camp' (camp can mean exaggerated or affected).
'by' is a charade indicator (letters next to each other).
'losing' suggests deleting specific letters.
'deposits' becomes 'lays' (I've seen this in another clue).
'delays' with 'lays' removed is 'de'.
'camp' put after 'de' is 'DECAMP'.
(Other definitions for decamp that I've seen before include "Move on" , "Mizzle" , "Fold tents and go" , "Make sudden breakaway" , "Run away (unseen)" .)