Take from mutt a luscious bone (5)
I believe the answer is:
talus
'bone' is the definition.
(I know that talus is a type of bone)
'take from mutt a luscious' is the wordplay.
'take from' indicates a hidden word (I've seen 'taken from' mean this).
'TALUS' can be found hidden inside 'mutt a luscious'.
(Other definitions for talus that I've seen before include "Foot's part" , "Yarns" , "Ankle bone" , "Ankle-bone" .)