Take heart from Beano and Dandy, too (2,4)
I believe the answer is:
as well
'too' is the definition.
(synonyms)
'take heart from beano and dandy' is the wordplay.
'take heart from' says to take the centre.
'and' is a charade indicator (letters next to each other).
'dandy' becomes 'swell' (both can informally mean excellent or satisfactory).
The central letter of 'beano' is 'a'.
'a'+'swell'='AS WELL'
(Other definitions for as well that I've seen before include "To boot" , "Also, additionally" , "with equal effect" , "on top" , "Appropriate" .)