Take it easy, since confined to bed (5)
I believe the answer is:
coast
'take it easy' is the definition.
(I've seen this in another clue)
'since confined to bed' is the wordplay.
'since' becomes 'as' (both can mean 'because').
'confined to' indicates putting letters inside.
'bed' becomes 'cot' (cot is a type of bed).
'as' put inside 'cot' is 'COAST'.
(Other definitions for coast that I've seen before include "float" , "Edge of landmass" , "Cruise" , "Sea border" , "Move easily without power" .)