Take lead from unusually large boss (4)
I believe the answer is:
umbo
'boss' is the definition.
(the boss on a shield)
'take lead from unusually large' is the wordplay.
'take lead from' means to remove the first letter.
'unusually large' becomes 'jumbo' (I've seen this before).
'jumbo' with its initial letter taken off is 'UMBO'.
(Another definition for umbo that I've seen is " Boss on a shield".)
I've seen this clue in The Independent.
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