Take no notice of Gore in trouble (6)
I believe the answer is:
ignore
'take no notice of' is the definition.
(I've seen this before)
'gore in trouble' is the wordplay.
'trouble' indicates an anagram.
'gore'+'in'='gorein'
'gorein' is an anagram of 'IGNORE'.
(Other definitions for ignore that I've seen before include "Fail to consider" , "Deliberately take no notice" , "Give no attention to" , "Slight" , "Region (anag)" .)