Take no notice of poor region (6)
I believe the answer is:
ignore
'take no notice of' is the definition.
(I've seen this before)
'poor region' is the wordplay.
'poor' indicates anagramming the letters.
'region' with letters rearranged gives 'IGNORE'.
(Other definitions for ignore that I've seen before include "Send to Coventry" , "Region (anag)" , "Turn a blind eye to" , "set aside" , "Deliberately take no notice" .)