Take no notice of some hanger-on, giving up (6)
I believe the answer is:
ignore
'take no notice of' is the definition.
(I've seen this before)
'some hanger-on giving up' is the wordplay.
'some' says the answer is hidden in the clue (some of the parts of the word are used).
'up' shows that the letters should be reversed in order (in down clue: letters go upwards).
'erongi' is hidden within 'hanger on giving'.
'erongi' written backwards gives 'IGNORE'.
(Other definitions for ignore that I've seen before include "Give no attention to" , "Pay no heed to" , "Pay no attention to, disdain" , "Pass over" , "Disregard - cut" .)