Take off and wander around East with maiden (6)
I believe the answer is:
remove
'take off' is the definition.
(thesaurus)
'wander around east with maiden' is the wordplay.
'wander' becomes 'rove' ('rove' can be a synonym of 'wander'**).
'around' is an insertion indicator.
'east' becomes 'e' ('E' can be a synonym of 'east').
'with' means one lot of letters go next to another.
'maiden' becomes 'm' (cricket abbreviation).
'e'+'m'='em'
'rove' enclosing 'em' is 'REMOVE'.
'and' is the link.
(Other definitions for remove that I've seen before include "class in a number of schools" , "Take away from present place, or get rid of" , "Get rid of, take away (6)" , "Subtract" , "Expel" .)