Take off for an excursion to the heart of Hampshire (5)
I believe the answer is:
strip
'take off' is the definition.
(stripping is a kind of taking off)
'an excursion to the heart of hampshire' is the wordplay.
'an excursion' becomes 'trip' (I've seen this before).
'to' says to put letters next to each other (I've seen this in other clues).
'the heart of' indicates the central letters.
The middle of 'hampshire' is 's'.
'trip' after 's' is 'STRIP'.
'for' acts as a link.
(Other definitions for strip that I've seen before include "runway" , "Team kit" , "Ribbon" , "Set of football clothes" , "Empty" .)