Take the edge off a large place (5)
I believe the answer is:
allay
'take the edge off' is the definition.
(thesaurus)
'a large place' is the wordplay.
'large' becomes 'l'.
'place' becomes 'lay' (laying is a kind of placing**).
'a'+'l'+'lay'='ALLAY'
(Other definitions for allay that I've seen before include "Diminish (fears/concern)" , "Assuage, ease" , "Mitigate" , "Diminish or end (fears)" , "Mollify or soothe, say fears" .)