Take weapons from spy chief after fresh raids (6)
I believe the answer is:
disarm
'take weapons from' is the definition.
(I've seen this in another clue)
'spy chief after fresh raids' is the wordplay.
'spy chief' becomes 'm' (M is the head of MI6 in the James Bond series).
'after' means one lot of letters go next to another.
'fresh' indicates anagramming the letters (a fresh re-ordering of the letters).
'raids' is an anagram of 'disar'.
'm' after 'disar' is 'DISARM'.
(Other definitions for disarm that I've seen before include "Remove suspicion" , "Take weapons from or make less hostile" , "Charm, win over" , "Remove weapons from" , "Take away weapons or make less angry" .)