Taking advantage of busy centre in front of goal (5)
I believe the answer is:
using
'taking advantage' is the definition.
(I've seen this in another clue)
'busy centre in front of goal' is the wordplay.
'centre' says to take the centre.
'front of' indicates taking the first letters (the letter at the front of the word).
The centre of 'busy' is 'us'.
The initial letter of 'goal' is 'g'.
'us'+'in'+'g'='USING'
'of' is the link.
(Other definitions for using that I've seen before include "Exploiting for one's own advantage" , "Putting into service" , "taking drugs" , "having recourse to" , "practice" .)