Talk idly about regular letters in biggest puzzle (6)
I believe the answer is:
jigsaw
'puzzle' is the definition.
(jigsaw puzzle is a type of puzzle)
I don't understand the remainder of the clue.
Can you help me to learn more?
(Other definitions for jigsaw that I've seen before include "Puzzle in which pieces must be reassembled" , "As pastime" , "Puzzle with pieces to assemble" , "Puzzle fittingly completed" , "Woodcutter" .)