Talk with woman, the mistress of the house (10)
I believe the answer is:
chatelaine
'mistress of the house' is the definition.
(I've seen this before)
'talk with woman' is the wordplay.
'talk' becomes 'chat' (chat can mean to talk).
'with' is a charade indicator (letters next to each other).
'woman' becomes 'elaine' ().
'chat'+'elaine'='CHATELAINE'
'the' is the link.
(Other definitions for chatelaine that I've seen before include "formerly the mistress of a castle" , "Castle keeper" , "Woman running a household" , "French mistress" , "Woman in charge of a large house" .)