Talking without interruption? Shut up! (6)
I believe the answer is:
intern
'shut up' is the definition.
(I've seen this before)
I can't explain the remainder of the clue.
Can you help me to learn more?
(Other definitions for intern that I've seen before include "Shut up" , "Confine the hospital doctor" , "House officer" , "put in jail" , "Hospital doctor (US)" .)