Target girl carrying nothing (4)
I believe the answer is:
goal
'target' is the definition.
(goal can mean a target or aim)
'girl carrying nothing' is the wordplay.
'girl' becomes 'gal' (synonyms).
'carrying' indicates putting letters inside.
'nothing' becomes 'O' (looks like zero - 0).
'gal' placed around 'o' is 'GOAL'.
(Other definitions for goal that I've seen before include "Aim and objective" , "Football score" , "Ambition for a score" , "posts and bar" , "Target, objective" .)