Tempo has changed penning Queen air (10)
I believe the answer is:
atmosphere
'air' is the definition.
('atmosphere' can be a synonym of 'air')
'tempo has changed penning queen' is the wordplay.
'changed' indicates anagramming the letters.
'penning' indicates putting letters inside.
'queen' becomes 'er' (abbreviation for Elizabeth Regina).
'tempo'+'has'='tempohas'
'tempohas' anagrammed gives 'atmosphe'.
'atmosphe' placed around 'er' is 'ATMOSPHERE'.
(Other definitions for atmosphere that I've seen before include "Air" , "Gas surrounding a planet" , "climate" , "blue?" , "We are always enveloped in this" .)