Tense and uneasy (2,4)

I think it could be either:

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2,4

on edge

(Other definitions for on edge that I've seen before include "Twitchy" , "Tense and irritable, very nervous" , "Cliff-top walker may be" , "Nervous and tense - close to cliff?" , "All agog" .)

I've seen this clue in The Guardian.

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